Cardiovascular
| Year | Description |
|---|---|
| 2002 | [Germany] 1st safety report of Autologous mononuclear BMCs의 selective intracoronary transplantation by Dr. Strauer |
| 2002 | [Germany] TOPCARE-AMI (Non-randomized trial) |
| 2002 | [Spain] Dr. Francisco Fernandez-Aviles, Jose (Non-randomized trial) |
| 2005 | [USA] the first postmortem findings was reported |
| 2006 | [Germany] first trial (TOPCARE-CHDI) for CMI patients was reported |
| 2006 | [Germany] BOOST trial (Randomized controlled trial) ? 60 subjects |
| 2006 | [Germany] REPAIR-AMI trial (Randomized double blind placebo controlled trial) Multicenter trial-204 patients were enrolled |
| 2006 | [Belgium] Janssens’ study (Negative results) |
| 2006 | [Norway] Lunde’s study (Negative results) |
| 2006 | [Germany] 18-mo follow-up study of BOOST trial (Negative results) |
| 2008 | 4 Meta-analysis were reported |
| 2009 | [Germany] Reported 60-mo long-term follow-up study (BALANCE study) |
| 2009 | [USA] the first 'off the shelf' MSC (Prochymal) study results was reported |
| 2009 | [Germany] 5-year follow-up study (Balance stidy) was reported |
| 2011 | [USA] Phase I study of injection of cardiac stem cell (SCIPIO) was reported |
| 2012 | [JAPAN] a hybrid cell therapy application (cardiac stem cells together with basic Fibroblast Growth Factor (bFGF) study was reported |
| 2012 | [USA] autologous cardiac-derived cells were applied in patients who developed LV dysfunction |
| 2012 | Optimization studies were reported, such as superior cell population, timing, dosing, delivery mode |
| 2015 | [USA] Negative results of individual patients data from 12 randomized trials of AMI was reported |
| 2015 | [USA] Transendocardial injections of allogeneic MPCs' feasiblity study was reported |
| Year | Description |
|---|---|
| 2001 | The first application of Myoblast in human |
| 2004 | Tried various administration of route -CABG/ LVAD/ surgery -Evidence of safety using NOGA system (3 articles) -Off-pump surgery methods used in cell injection(2 articles) |
| 2005 | Reported 3 Randomized controlled studies -[USA] The first report of prospective RCT -[Germany] 2 RCTs |
| 2007 | Long-term safety and efficacy studies were reported (6 articles) |
| 2011 | Combination cell injection or cell injection with other treatment methods -BMC+Myoblast -BMC+MSC -BMC+CRT |
| 2012 | Randomized controlled studies were reported using novel cell -1st report applied CDC -1st RCT using ALDH cell |
| Year | Description |
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| Year | Description |
|---|---|
| 2006 | 4 clinical trials were reported in patients with Dilated CMP -PBSC intramyocardial injection by thoracotomy -[India] ABCD trial (RCT) |
| 2008 | [USA] 1st safety and efficacy report MSC injection |
| 2008 | [Russia] IC injection of MSC |
| 2008 | [Malaysia] Cryopreservation protocol for the MSC |
| 2010 | [India] Reported 3-year follow-up results of ABCD trial |
| 2011 | [Slovenia] IC injection of PBSC (CD34 cell) ? survival analysis -1-year FU(2011) -5-year FU(2013) |
| 2011 | [UK] REGENERATE-DCM protocol ? placebo controlled study |
| 2012 | [Japan] Tissue engineered Myoblast sheet |
| Year | Description |
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| Year | Description |
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